Research Facility


The BRNSS-CRC has pooled resources of all the institutions and affiliates of B R Nahata Smiriti Sansthan. Its exclusive lab ‘Drug Development and Industrial Pharmacy Lab’ located at BRNCP has a pool of more than 50 researchers. Philosophy BRNSS-CRC is aimed at providing cost-effective and fast-track solutions in Pharmaceutical, Cosmetic, Herbal and Nutraceutical Technology. Functioning The Director-BRNCP under the guidance of the Chairman-BRNSS controls BRNSS-CRC. It operates through following group leaders

  • Cosmeceuticals & Nutraceuticals
  • Herbal Drug Research & Green Pharmacy
  • Product Development & Production Trouble Shooting
  • Quality Audit & Regulatory Affairs
  • Analytical Development & Synthetic Chemistry
  • Clinical Research
  • Corporate Training and Placement

Click here to download Research facility Application Form

 Services Available in Department of Pharmacology:

S. No.

Service available Models

1.

Anti Diabetic Activity Streptozotocin induced Diabetes
Alloxan induced Diabetes

2.

Diabetic Complications Streptozotocin induced Diabetic Complications
Alloxan induced Diabetic Complications
Diabetic Wound Healing
Diabetic Nephropathy
Diabetic Stress

3.

Diuretic  Activity Urine Collection Models bymetabolic cages

4.

Analgesic  Activity Hot plate
Radiant Heat or Tail Flik
Tail Immersion Test
Acetic Acid Induced writhing Test

5.

Anti-inflammatory Activity Caragenan  Induced Paw edema
 Granuloma Pouch Technique

6.

Cardio toxicity Isopenaline Induced
Adreamine Induced
Imipramine Induced
Doxorubicin Induced

7.

Anti Arthritic Activity Pristane induced arthritis
Freund’s adjuvant induced arthritis model

8.

Anti Hyperlipidemic Activity High Fat Diet Induced Hyperlipidemia
Diabetes induced Hyperlipidemia
Cholesterol induced  Hyperlipidemia

9.

Hepatoprotective Activity CClInduced
Paracetamol Induced
Thiacetamide Induced
Alcohol Induced

10.

Anti  Stress Activity Forced Swim
Chronic Immobilization stress
Acute Immobilization stress
Cold Stress

11.

CNS Activities Anti Anxiety Acivity
Anti Depression acticity
Locomotor Activity
Memory enhancing Activity
Muscle relaxant Activity
Central Analgesic activity

12.

Antioxidant Activity NBT Method
MDA Method

13.

Wound Healing Activity Excision Wound Healing Model
Incision Wound Healing Model
Dead space Wound Healing Model
Burn  Wound Healing Model (Cold Burn, Hot Burn, Acid Burn)

14.

Nephro toxicity Lithium Induced
Cisplatin Induced

15.

Oxidative Stress Streptozotocin induced Oxidative Stress
Alloxan induced Oxidative Stress

16.

Immunomodulatory Activities Sheep RBC Induced Immune Stimulation
Pristane induced Immune Stimulation
Freund’s adjuvant induced Immune Stimulation

17.

Anti Fertility Activity

18.

Gastro paresis Char coal Meal Test
Phenol Red Model
Gastric Emptying Rate Testing

19.

Bio assay on isolated tissue Four Point  Bio assay
Graphical Bio assay
Matching Bio assay
Three Point Bio assay
Agonist Antagonist Bio assay

20.

Diabetes  insipidus Lithium Induced

21.

Silicosis/ Respiratory / Inhalation Activities Slate pain dust induced
Cement
Dust Induced
Pollutant Induced

22.

Anti Diarrheal Activity Caster oil induced Diarrhea

23.

Drug interactions

24.

Toxicity studies  (Acute / Chronic)

25.

Blood Biochemistry

26.

Urine Biochemistry

27.

Liver biochemistry

 

Major Equipments

Name of Equipments

Qty

Details

IR Moisture Balance 1 Amekette
Electronic Balance 10 Shimadzuan Merck
BOD Incubator 1 Labtech & Dolphin
Disintegration App. 1 Electrolab
UV Spectrophotometer 5 Shimadzu & Elico
Dissolution Rate Test App. 1 TDT-06T
Brookfield Viscometer 2 Amekette
Gas Chromatography Eq. 2 Netal
HPTLC 1 Camag
HPLC 2 Merck & Waters
Trino CXR IIIw/Photo ATTC 2 Labomad
Sonicator 2 MAC
Environmental Test Chamber 3 Remi
Rotary Shaker 1 Remi
Digital Camera 1 E-Cam
Tablet Machine-Electric 1 Kambert
FTIR 1 Shimadzu
Liquid Filling Machine 1 Dolphin
Tray Drier 1 Dolphin
Double Cone Vlender 1 Dolphin
Physiograph three channel 1 Dellsoft
Sterotaxic Unit 1 INC
Laboratory Spray Drier 1 Labultima
Fluid Bed Dryer 1 Electrolab
Auto Analyser 1 Aspen
AAS 1 Shimadzu
DSC 1 Shimadzu
Molecular Modeling workstation 1 Dell

  Solutions Offered

  • Designing of Production and Testing Facilities
  • Product Development
  • Analytical Method Development
  • Stability Studies as per ICH guidelines
  • Pharmacological & Clinical studies
  • Microbial Studies
  • Process Optimization and SOP writing
  • Patent writing and processing
  • Product promotion literature
  • Production trouble shooting
  • Investigation of market complaints
  • Documentation and Quality Audits for ISO, US-FDA and WHO-GMP certification

Ongoing Projects

  • Drug Development Studies on Momordica indica
  • Drug Development Studies on Solanum xanthocarpum
  • Drug Development and Export Potential Studies on Ashwagandha
  • Bioprofiling and Chemoprofiling of Bougainvillea glabra
  • Wound Healing Activity of Achyrenthes aspera
  • Studies on Thuja oxidentalis for Hepatoprotective and Anti-Malarial Activities
  • Formulation and Evaluation of Phytosomes
  • Aerosolized Liposomal Technology for Pulmonary Delivery of Anti-Tubercular Drugs
  • Development of DC Excipients
  • Soft Gelatin Technology for Suppositories
  • Studies on the Dosage Form Applications of Crystals
  • Formulation Development of Anti-Emetic Drugs in Fast Dissolving Dosage Forms
  • Preparation and Characterization of Gugglusomes of Anti-Inflammatory Drugs
  • Oral Absorption of Niosomes
  • Self-Emulsifying Formulations
  • Floating Tablets
  • Effervescent Technology for Nutraceuticals & Pharmaceuticals
  • Quality Audit of Chyawanprash
  • Bio-Technological Approach for the Production of Plant Constituents With Special Reference to Anti-Malarial Activity
  • Biotechnological Studies on Asava and Aristha
  • Pharmaceutical Aspects of Mahasudarshan Churna
  • Pharmaceutical Screening on Cow’s Urine
  • Corneal Transport of Ciprofloxacin
  • Estimation of Laprasidone in Tablet Formulation by UV Spectroscopy
  • Estimation of Laprasidone in Tablet Formulation by UV Spectroscopy
  • Novel Floating System
  • Synthesis of Novel Quinoline Derivative as Possible Anti-Tubercular Agents
  • Pharmaceutical Applications of Novel Herbal Mucilages
  • Formulation and Evaluation of Curcumin Microspheres